GBA2 Polyclonal antibody, PBS Only

GBA2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17164-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 17164-1-AP (same clone as 17164-1-PBS)

  Human placenta tissue were subjected to SDS PAGE followed by western blot with 17164-1-AP (GBA2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17164-1-PBS in a different storage buffer formulation.

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Product Information

17164-1-PBS targets GBA2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: GBA2 fusion protein Ag10606
• Full Name: glucosidase, beta (bile acid) 2
• Calculated Molecular Weight: 927 aa, 105 kDa
• Observed Molecular Weight: 105 kDa
• GenBank Accession Number: BC011363
• Gene Symbol: GBA2
• Gene ID (NCBI): 57704
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

GBA2(Non-lysosomal glucosylceramidase) is also named as KIAA1605,NLGase and belongs to the non-lysosomal glucosylceramidase family.It catalyzes the conversion of glucosylceramide to free glucose and ceramide and is involved in sphingomyelin generation and prevention of glycolipid accumulation.GBA2 contains a putative membrane-spanning domain and 2 potential N-glycosylation sites. However, glycosidase treatment indicated that GBA2 is not a glycoprotein(PMID:11489889).It has 3 isoforms produced by alternative splicing.