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- KD/KO Validated
GATA4-Specific Polyclonal antibody
GATA4-Specific Polyclonal Antibody for WB, ELISA
Cat no : 19530-1-AP
|Positive WB detected in||HepG2 cells, mouse liver tissue, mouse heart tissue, rat heart tissue, PC-3 cells, NIH/3T3 cells|
|Western Blot (WB)||WB : 1:1000-1:6000|
|Sample-dependent, check data in validation data gallery|
19530-1-AP targets GATA4-Specific in WB, IP, IHC, IF, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat, monkey|
|Host / Isotype||Rabbit / IgG|
|Full Name||GATA binding protein 4|
|Calculated molecular weight||45 kDa|
|Observed molecular weight||45 kDa|
|GenBank accession number||NM_002052|
|Gene ID (NCBI)||2626|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
What is the molecular weight of GATA4? Is GATA4 post-translationally modified?
The molecular weight of GATA4 is 48 kDa. GATA4 can be phosphorylated, which regulates its activity (PMID: 10788492).
What is the subcellular localization of GATA4?
GATA4 localizes to the nucleus. The nuclear localization motif is present in the C-terminal part of GATA4 (PMID: 9079680).
What is the tissue expression pattern of GATA4?
GATA4 was initially identified as a cardiac transcription factor important for the development of the heart and as one of the earliest transcription factors expressed in developing cardiac cells. However, GATA4 is expressed in numerous organs such as the liver, lung, gonads, and small intestine (PMID: 8455608).
Divergent transcriptional regulation of astrocyte reactivity across disorders.
Clin Transl Med
Bmi-1-RING1B prevents GATA4-dependent senescence-associated pathological cardiac hypertrophy by promoting autophagic degradation of GATA4.
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4.
Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR26b-5p and miR-140-3p binding to Gata4.
J Bone Miner Res
Bmi-1 Overexpression Improves Sarcopenia Induced by 1,25(OH)2 D3 Deficiency and Downregulates GATA4-Dependent Rela Transcription
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.