Anti-Mouse FceR1 (MAR-1)

FceR1 Monoclonal Antibody for FC

Host / Isotype

Armenian Hamster / IgG

Reactivity

Mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

MAR-1

Cat no : 65091-1-Ig

Synonyms

Fce1a, fcepsilonri, FceR1, Fcer1a, FcERI, Fcr 5

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Validation Data Gallery

• 

  FC experiment of MC/9 using 65091-1-Ig

  1X10^6 MC/9 cells were surface stained with 0.25 ug Anti-Mouse FceR1 (65091-1-Ig, Clone: MAR-1) and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (green), or stained with 0.25 ug Armenian Hamster IgG isotype control and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) at dilution 1:1000 (black). Cells were not fixed.

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Tested Applications

• Positive FC detected in: MC/9 cells

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

65091-1-Ig targets FceR1 in FC applications and shows reactivity with Mouse samples.

• Tested Reactivity: Mouse
• Host / Isotype: Armenian Hamster / IgG
• Class: Monoclonal
• Type: Antibody
• Immunogen: N/A
• Full Name: Fc receptor, IgE, high affinity I, alpha polypeptide
• GenBank Accession Number: BC125455
• Gene Symbol: FceR1
• Gene ID (NCBI): 14125
• RRID: AB_2918394
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Affinity purification
• Storage Buffer: PBS with 0.1% sodium azide, pH 7.3.
• Storage Conditions: Store at 2-8°C. Stable for one year after shipment.

Background Information

Fc epsilon Receptor I alpha (FceRIa) is a single-pass type I membrane protein which contains 2 immunoglobulin-like domains. FceRIa forms a tetrameric complex with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316).