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Fc epsilon RI alpha Recombinant antibody, PBS Only

Fc epsilon RI alpha Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241848D1

Cat no : 84662-3-PBS

Synonyms

FCER1A, FceRIa, FcERI, Fc-epsilon RI-alpha, FCE1A

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using Fc epsilon RI alpha Recombinant antibody (84662-3-RR)

    WB analysis using 84662-3-RR (same clone as 84662-3-PBS)

    Human testis was subjected to SDS PAGE followed by western blot with 84662-3-RR (Fc epsilon RI alpha antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84662-3-PBS in a different storage buffer formulation.

Product Information

84662-3-PBS targets Fc epsilon RI alpha in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein
Full Name Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Calculated Molecular Weight30kDa
Observed Molecular Weight55-65 kDa
GenBank Accession NumberNM_001387280.1
Gene Symbol Fc Epsilon RI Alpha
Gene ID (NCBI) 2205
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Fc fragment of IgE, high affinity I, receptor for, alpha polypeptide, also known as high affinity immunoglobulin epsilon receptor subunit alpha, FCER1A and FCE1A, is a single-pass type I membrane protein which contains 2 immunoglobulin-like domains. FCER1A is a subunit of the IgE receptor, which is composed of one glycosylated alpha (FCER1A), one beta (FCER1B), and two gamma (FCER1G) subunits. The high affinity IgE receptor plays a central role in allergic disease, coupling allergen and mast cells to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The calculated molecular weight of FCER1A is 30 kDa, the 55- to 70-kDa bands detected by this antibody are probably caused by heterogeneous glycosylation (PMID: 11344350; 12671054).