FURIN Monoclonal antibody, PBS Only

FURIN Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67481-1-PBS
Clone No.1D1B9

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse

Applications

WB, IHC, Indirect ELISA

Dibasic processing enzyme, FUR, FURIN, PACE, PCSK3, SPC1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

67481-1-PBS targets FURIN in WB, IHC, Indirect ELISA applications and shows reactivity with Human, Mouse samples.

Tested Reactivity Human, Mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen FURIN fusion protein Ag13313 Predict reactive species
Full Name furin (paired basic amino acid cleaving enzyme)
Calculated Molecular Weight 87 kDa
Observed Molecular Weight 90-110 kDa
GenBank Accession NumberBC012181
Gene Symbol FURIN
Gene ID (NCBI) 5045
RRIDAB_2882708
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP09958
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

FURIN, also named as FUR, PACE, PCSK3, SPC1, Kex2p, is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif. Furin is synthesized as an inactive zymogen that may minimize the occurrence of premature enzymatic activity that would lead to alternative protein activation or degradation. Glycosylation and other post-translational modifications can make the pre-pro furin run at 100-110 kDa, the mature furin at 98-95 kDa and shed furin at 90 kDa.

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