FKBP1A Polyclonal antibody, PBS Only

• Featured Product
• KD/KO Validated

FKBP1A Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10273-1-PBS

Synonyms

FKBP12, FKBP1, FKBP 1A, FK506-binding protein 1A, Calstabin-1

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Validation Data Gallery

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  WB analysis using 10273-1-AP (same clone as 10273-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 10273-1-AP (FKBP1A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10273-1-PBS in a different storage buffer formulation.

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  WB analysis using 10273-1-AP (same clone as 10273-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10273-1-AP (FKBP1A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10273-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 10273-1-AP (same clone as 10273-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 10273-1-AP (FKBP1A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10273-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 10273-1-AP (same clone as 10273-1-PBS)

  Immunohistochemical analysis of paraffin-embedded normal colon slide using 10273-1-AP (FKBP1A antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10273-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 10273-1-AP (same clone as 10273-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human normal colon slide using 10273-1-AP (FKBP1A antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10273-1-PBS in a different storage buffer formulation.

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Product Information

10273-1-PBS targets FKBP1A in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FKBP1A fusion protein Ag0406
• Full Name: FK506 binding protein 1A, 12kDa
• Calculated Molecular Weight: 12 kDa
• Observed Molecular Weight: 12 kDa
• GenBank Accession Number: BC001925
• Gene Symbol: FKBP1A
• Gene ID (NCBI): 2280
• RRID: AB_2231588
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

FKBP1A(FK506-binding protein 1A) is also named as FKBP1, FKBP12 and belongs to the FKBP-type PPIase family.It keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.