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  • KD/KO Validated

FGFBP1 Polyclonal antibody

FGFBP1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, ELISA, IF

Conjugate

Unconjugated

Cat no : 25006-1-AP

Synonyms

FGF BP1, FGF BP, FGF binding protein 1, 17 kDa heparin-binding growth factor-binding protein, 17 kDa HBGF-binding protein



Tested Applications

Positive IHC detected inhuman skin cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

25006-1-AP targets FGFBP1 in WB, IHC, ELISA, IF applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FGFBP1 fusion protein Ag6357
Full Name fibroblast growth factor binding protein 1
Calculated Molecular Weight 26 kDa
GenBank Accession NumberBC003628
Gene Symbol FGFBP1
Gene ID (NCBI) 9982
RRIDAB_2879843
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FGFBP1, also named as HBP17, is prominent for its role as the chaperone for fibroblast growth factor-2 (FGF-2), which plays a crucial role in angiogenesis as well as promoting tumor growth. HBp17/FGFBP-1 has been proposed as a candidate biomarker for a number of cancers since it is frequently found to be elevated in many cancer types including in the tissue and cell lines of oral squamous cell carcinomas (OSCC).

Protocols

Product Specific Protocols
IHC protocol for FGFBP1 antibody 25006-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIF

Mol Cell

A transient transcriptional activation governs unpolarized-to-polarized morphogenesis during embryo implantation

Authors - Xuehui Lyu
humanWB,IHC

Front Immunol

FGFBP1 as a potential biomarker predicting bacillus Calmette-Guérin response in bladder cancer

Authors - Fei Li
mouseWB,IHC

Am J Cancer Res

Type-2 11β-hydroxysteroid dehydrogenase promotes the metastasis of colorectal cancer via the Fgfbp1-AKT pathway.

Authors - Jin Chen
  • KD Validated
humanWB,IHC

Transl Oncol

Identification of metastasis-associated exoDEPs in colorectal cancer using label-free proteomics.

Authors - Xinlu Liu
humanWB

Pharm Biol

Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro

Authors - Yang Yang
human,mouseWB

Cell Death Dis

Inhibitory effect of the novel tyrosine kinase inhibitor DCC-2036 on triple-negative breast cancer stem cells through AXL-KLF5 positive feedback loop

Authors - Yingying Shen