FBXO7 Polyclonal antibody, PBS Only

FBXO7 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 10696-1-PBS

Synonyms

PARK15, FBXO 7, FBX7, FBX07, FBX

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Validation Data Gallery

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  WB analysis using 10696-1-AP (same clone as 10696-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 10696-1-AP (FBXO7 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10696-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach using 10696-1-AP (same clone as 10696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 10696-1-AP (FBXO7 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10696-1-PBS in a different storage buffer formulation.

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  IHC staining of human intrahepatic cholangiocarcinoma using 10696-1-AP (same clone as 10696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 10696-1-AP (FBXO7 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10696-1-PBS in a different storage buffer formulation.

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Product Information

10696-1-PBS targets FBXO7 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: FBXO7 fusion protein Ag1035
• Full Name: F-box protein 7
• Calculated Molecular Weight: 59 kDa
• Observed Molecular Weight: 59-75 kDa
• GenBank Accession Number: BC008361
• Gene Symbol: FBXO7
• Gene ID (NCBI): 25793
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

FBXO7, also named as FBX7, is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO7 recognizes BIRC2 and DLGAP5. It function in phosphorylation-dependent ubiquitination.