|It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
|Sample-dependent, check data in validation data gallery
The immunogen of 22542-1-AP is EGFR (N-terminal) Fusion Protein expressed in E. coli.
|Host / Isotype
|Rabbit / IgG
|EGFR (N-terminal) fusion protein Ag16543
|epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
|Calculated molecular weight
|1210 aa, 134 kDa
|GenBank accession number
|Gene ID (NCBI)
|Antigen affinity purification
|PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
|Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.
ERBB1, also mamed as EGFR, is a receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. ERBB1 is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with C-SRC and CTNNB1/beta-catenin. Isoform 2/truncated isoform of ERBB1 may act as an antagonist. EGFR is associated with lung cancer. The antibody can recognize all the isoforms.
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Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells.
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Vitamin A maintains the airway epithelium in a murine model of asthma by suppressing glucocorticoid-induced leucine zipper.
Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection.
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Potential mechanisms underlying the promoting effects of 3D collagen scaffold culture on stemness and drug resistance of glioma cells