• Featured Product
  • KD/KO Validated

DYNC1I1 Polyclonal antibody

DYNC1I1 Polyclonal Antibody for IHC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 13808-1-AP

Synonyms

DH IC 1, DNCI1, DNCIC1, DYNC1I1



Tested Applications

Positive WB detected inU-87 MG cells, mouse brain tissue, rat brain tissue
Positive IHC detected inhuman gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:8000
Immunohistochemistry (IHC)IHC : 1:50-1:400
Sample-dependent, check data in validation data gallery

Product Information

13808-1-AP targets DYNC1I1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DYNC1I1 fusion protein Ag4810
Full Name dynein, cytoplasmic 1, intermediate chain 1
Calculated molecular weight 645 aa, 71 kDa
Observed molecular weight 71 kDa
GenBank accession numberBC022540
Gene symbol DYNC1I1
Gene ID (NCBI) 1780
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Protocols

Product Specific Protocols
WB protocol for DYNC1I1 antibody 13808-1-APDownload protocol
IHC protocol for DYNC1I1 antibody 13808-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IF,IHC

Oncogene

Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.

Authors - Heidi A Neubauer
  • KD Validated
humanWB

Front Mol Neurosci

MFN2 Deficiency Impairs Mitochondrial Transport and Downregulates Motor Protein Expression in Human Spinal Motor Neurons

Authors - Yongchao Mou
mouseWB

Neurobiol Dis

Pain sensitivity related to gamma oscillation of parvalbumin interneuron in primary somatosensory cortex in Dync1i1-/- mice

Authors - Zhongzhao Guo
  • KO Validated

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Q (Verified Customer) (03-22-2021)

An OK antibody to detect DIC1, although the signal is a little weak and strong ECL is required.

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: mouse primary neurons
DYNC1I1 Antibody Western Blot validation (1:500 dilution) in mouse primary neurons (Cat no:13808-1-AP)