|Positive WB detected in||U-87 MG cells, mouse brain tissue, rat brain tissue|
|Positive IHC detected in||human gliomas tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:1000-1:8000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:400|
|Sample-dependent, check data in validation data gallery|
13808-1-AP targets DYNC1I1 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||DYNC1I1 fusion protein Ag4810|
|Full Name||dynein, cytoplasmic 1, intermediate chain 1|
|Calculated molecular weight||645 aa, 71 kDa|
|Observed molecular weight||71 kDa|
|GenBank accession number||BC022540|
|Gene ID (NCBI)||1780|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.
Front Mol Neurosci
MFN2 Deficiency Impairs Mitochondrial Transport and Downregulates Motor Protein Expression in Human Spinal Motor Neurons
Pain sensitivity related to gamma oscillation of parvalbumin interneuron in primary somatosensory cortex in Dync1i1-/- mice
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Q (Verified Customer) (03-22-2021)
An OK antibody to detect DIC1, although the signal is a little weak and strong ECL is required.