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DPYD Polyclonal antibody, PBS Only

DPYD Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 25690-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse liver tissue using DPYD Polyclonal antibody (25690-1-AP)

    WB analysis of mouse liver using 25690-1-AP (same clone as 25690-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 25690-1-AP (DPYD antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25690-1-PBS in a different storage buffer formulation.

Product Information

25690-1-PBS targets DPYD in WB, Indirect ELISA applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DPYD fusion protein Ag20885
Full Name dihydropyrimidine dehydrogenase
Calculated Molecular Weight 1025 aa, 111 kDa
Observed Molecular Weight111 kDa
GenBank Accession NumberBC008379
Gene Symbol DPYD
Gene ID (NCBI) 1806
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.