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  • KD/KO Validated

DPEP1 Polyclonal antibody

DPEP1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, FC, IHC, ELISA

Conjugate

Unconjugated

Cat no : 12222-1-AP

Synonyms

Dehydropeptidase I, Dipeptidase 1, dipeptidase 1 (renal), DPEP1, hRDP, MBD1, MDP, Microsomal dipeptidase, RDP, Renal dipeptidase



Tested Applications

Positive WB detected inHepG2 cells, mouse liver tissue, HEK-293 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:5000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

12222-1-AP targets DPEP1 in WB, FC, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, monkey
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DPEP1 fusion protein Ag2907
Full Name dipeptidase 1 (renal)
Calculated Molecular Weight 411 aa, 46 kDa
Observed Molecular Weight 46 kDa
GenBank Accession NumberBC017023
Gene Symbol DPEP1
Gene ID (NCBI) 1800
RRIDAB_2877837
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DPEP1(Dipeptidase 1) is also named as MDP, RDP and belongs to the peptidase M19 family. It is a glycoprotein that plays an important role in the regulation of leukotriene activity. DPEP1 converts lekotriene D4 to leukotriene E4.

Protocols

Product Specific Protocols
WB protocol for DPEP1 antibody 12222-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouse,humanWB

Cell

Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver.

Authors - Saurav Roy Choudhury
  • KO Validated
humanWB,FC

Sci Adv

Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.

Authors - Anne von Mässenhausen
  • KD Validated
humanIHC

Sci Adv

Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury.

Authors - Arthur Lau
monkey

J Clin Invest

Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.

Authors - Arthur Lau
mouseWB

Nat Commun

A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.

Authors - Yuting Guan
  • KO Validated
mouse,humanWB

Int Immunopharmacol

Dipeptidase 1 promotes ferroptosis in renal tubular epithelial cells in diabetic nephropathy via inhibition of the GSH/GPX4 axis

Authors - Yan Li