DRP1 (N-terminal) Polyclonal antibody

DRP1 (N-terminal) Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, ELISA

Conjugate

Unconjugated

Cat no : 26187-1-AP

Synonyms

DLP1, DNM1L, DNM1L,DLP1, DRP1, DRP1 (N-terminal), dynamin 1 like, Dynamin 1 like protein, Dynamin like protein



Tested Applications

Positive WB detected inmouse brain tissue, rat brain tissue
Positive IP detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 5 publications below

Product Information

26187-1-AP targets DRP1 (N-terminal) in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DRP1 (N-terminal) fusion protein Ag24249
Full Name dynamin 1-like
Calculated Molecular Weight 736 aa, 82 kDa
Observed Molecular Weight 70-78 kDa
GenBank Accession NumberBC024590
Gene Symbol DRP1
Gene ID (NCBI) 10059
RRIDAB_2880417
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

DNM1L(Dynamin-1-like protein) , also known as dynamin-related protein 1 (DRP1), belongs to the dynamin family of large GTPases that mediate membrane remodeling during a variety of cellular processes. DNM1L has an important role in the division of growing mitochondria and peroxisomes and also mediates outer mitochondrial membrane fission in mammalian cells. DNM1L is ubiquitously expressed with abundant expression in skeletal muscle, heart, kidney and brain.Variable isoforms of DNM1L have been reported in a tissue-specific manner due to the alternative splicing.

Protocols

Product Specific Protocols
WB protocol for DRP1 (N-terminal) antibody 26187-1-APDownload protocol
IP protocol for DRP1 (N-terminal) antibody 26187-1-APDownload protocol
FC protocol for DRP1 (N-terminal) antibody 26187-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle

Mol Cell

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation

Authors - Stephanie Pei Tung Yiu
humanWB

EMBO Mol Med

High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts.

Authors - Emma Cretin
humanWB

Biochem Biophys Res Commun

DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.

Authors - Chang Lu
humanWB

Asian J Androl

Mannose inhibits the growth of prostate cancer through a mitochondrial mechanism.

Authors - Yu-Lin Deng
WB

Environ Pollut

Mitochondrial dynamics disruption: Unraveling Dinotefuran's impact on cardiotoxicity

Authors - Jiaping Zhu
mouseWB

Inflamm Res

Transcriptomic analysis reveals molecular characterization and immune landscape of PANoptosis-related genes in atherosclerosis

Authors - Zhipeng Zheng