Validation Data Gallery
|Positive WB detected in||mouse heart tissue, MCF-7 cells, BxPC-3 cells, mouse colon tissue, rat heart tissue, NIH/3T3 cells|
|Positive IHC detected in||human breast cancer tissue, human ovary tissue, human skin cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||BxPC-3 cells|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
14667-1-AP targets Decorin in WB, IHC, IF applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat, hamster|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Decorin fusion protein Ag6328|
|Calculated molecular weight||359 aa, 40 kDa|
|Observed molecular weight||70 kDa, 45-48 kDa|
|GenBank accession number||BC005322|
|Gene ID (NCBI)||1634|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Decorin is a member of the small leucine-rich proteoglycan family of proteins. Decorin interacts with type I collagen fibrils, thereby influencing the kinetics of fibril formation and the distance between adjacent collagen fibrils. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis.
J Cell Physiol
Priming integrin α5 promotes human dental pulp stem cells odontogenic differentiation due to extracellular matrix deposition and amplified extracellular matrix-receptor activity.
Am J Physiol Lung Cell Mol Physiol
Identification of CAV1 and DCN as potential predictive biomarkers for lung adenocarcinoma.
Hypomorphic mutations of TRIP11 cause odontochondrodysplasia.
Negative impact of hyperglycaemia on mouse alveolar development.
Effects of polysaccharide from Physalis alkekengi var. francheti on liver injury and intestinal microflora in type-2 diabetic mice.
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Iram (Verified Customer) (06-13-2022)
Excellent antibody for western blotting
Balawant (Verified Customer) (05-08-2022)
I have used this antibody. This antibody is excellent, and I used it for western blotting. The dilution of 1:1000 is functioning well.
Susmita (Verified Customer) (09-17-2020)
Antibody is working very good for WB