- Featured Product
- KD/KO Validated
COX2/ Cyclooxygenase 2/ PTGS2 Monoclonal antibody, PBS Only
COX2/ Cyclooxygenase 2/ PTGS2 Monoclonal Antibody for WB, IHC, IF-P, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse
Applications
WB, IHC, IF-P, ELISA
Conjugate
Unconjugated
CloneNo.
3G2B9
Cat no : 66351-1-PBS
Synonyms
Validation Data Gallery
Product Information
66351-1-PBS targets COX2/ Cyclooxygenase 2/ PTGS2 in WB, IHC, IF-P, ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | COX2/ Cyclooxygenase 2/ PTGS2 fusion protein Ag24721 |
Full Name | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
Calculated Molecular Weight | 604 aa, 68 kDa |
Observed Molecular Weight | 66-70 kDa |
GenBank Accession Number | BC013734 |
Gene Symbol | COX2/PTGS2 |
Gene ID (NCBI) | 5743 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. |
Background Information
COX2 (Prostaglandin G/H synthase 2, PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72-74 kDa and the aglycosylated is 66 kDa (PMID:19656660). It also expresses a band of 39 kDa after unspecific cleavage (PMID:17509125). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains (PMID:14724276).