CLSTN3 Monoclonal antibody, PBS Only (Detector)

CLSTN3 Monoclonal Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A3C3

Cat no : 68855-2-PBS

Synonyms

Alc-beta, alcbeta, Alcadein-beta, Alcadein beta, Alc beta

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Validation Data Gallery

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  Cytometric bead array standard curve of MP50250-1

  Cytometric bead array standard curve of MP50250-1, CLSTN3 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68855-1-PBS. Detection antibody: 68855-2-PBS. Standard:Ag14897. Range: 0.391-25 ng/mL.

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  Cytometric bead array standard curve of MP50250-2

  Cytometric bead array standard curve of MP50250-2, CLSTN3 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68855-3-PBS. Detection antibody: 68855-2-PBS. Standard:Ag14897. Range: 3.125-50 ng/mL.

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Product Information

68855-2-PBS targets CLSTN3 as part of a matched antibody pair:

MP50250-1: 68855-1-PBS capture and 68855-2-PBS detection (validated in Cytometric bead array)

MP50250-2: 68855-3-PBS capture and 68855-2-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: CLSTN3 fusion protein Ag14897
• Full Name: calsyntenin 3
• Calculated Molecular Weight: 968 aa, 107 kDa
• GenBank Accession Number: BC039075
• Gene Symbol: CLSTN3
• Gene ID (NCBI): 9746
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G Magarose purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Calsyntenins, also called alcadeins, are cadherin superfamily proteins first identified as synaptic proteins (PMID: 11161476; 12498782). Calsyntenins are type I transmembrane proteins with extracellular domains containing two cadherin repeats and an LNS (laminin, neurexin, sex hormone-binding globulin) domain (PMID: 24613359). Calsyntenin-3 (CLSTN3, also known as alcadein-beta) is a synapse-organizing protein that promotes the development of synapses. It is a postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (PMID: 25352602; 24613359).