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CFP Monoclonal antibody, PBS Only

CFP Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, pig, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1D5A9

Cat no : 66788-1-PBS

Synonyms

BFD, CFP, Complement factor P, complement factor properdin, PFC, PFD, PROPERDIN

Validation Data Gallery

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  • Western Blot (WB) analysis of Jurkat cells using CFP Monoclonal antibody (66788-1-Ig)

    WB analysis of Jurkat using 66788-1-Ig (same clone as 66788-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66788-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human plasma using CFP Monoclonal antibody (66788-1-Ig)

    WB analysis of human plasma using 66788-1-Ig (same clone as 66788-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 66788-1-Ig (CFP antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66788-1-PBS in a different storage buffer formulation.

Product Information

66788-1-PBS targets CFP in WB, Indirect ELISA applications and shows reactivity with Human, pig, rat samples.

Tested Reactivity Human, pig, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CFP fusion protein Ag9798
Full Name complement factor properdin
Calculated Molecular Weight 469 aa, 51 kDa
Observed Molecular Weight 50 kDa, 100 kDa, 150 kDa
GenBank Accession NumberBC015756
Gene Symbol CFP
Gene ID (NCBI) 5199
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105). In plasma, properdin exists as dimers, trimers or tetramers.