CDON Polyclonal antibody

CDON Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Publications

1

Cat no : 17634-1-AP

Synonyms

CDO, CDON, Cdon homolog (mouse), ORCAM

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Validation Data Gallery

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  WB analysis using 17634-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 17634-1-AP (CDON antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HeLa cells, SH-SY5Y cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below

Product Information

17634-1-AP targets CDON in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Cited Reactivity: rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: CDON fusion protein Ag11904
• Full Name: Cdon homolog (mouse)
• Calculated Molecular Weight: 1287 aa, 140 kDa
• Observed Molecular Weight: 190 kDa
• GenBank Accession Number: BC098583
• Gene Symbol: CDON
• Gene ID (NCBI): 50937
• RRID: AB_10804050
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Cell adhesion molecule-related/down-regulated by oncogenes (CDO), also known as CDON, is an orphan cell surface receptor belonging to the immunoglobulin superfamily. CDON possesses five Ig-like domains, with three FNIII-like repeats in the extracellular region, a transmembrane domain, and a cytoplasmic tail. CDON plays an important role in the active regulation of myogenic differentiation. The predicted molecular weight of CDON is 139 kDa, and the bands of 190 kDa may be due to glycosylation

Publications

Species	Application	Title
rat	WB	Microb Pathog; Staphylococcal enterotoxin B exposed to pregnant rats inhibits the hedgehog signaling pathway in thymic T lymphocytes of the offspring; Authors - Jia-Bao Zhao