Anti-Mouse NCAM1/CD56 Rabbit Recombinant Antibody, PBS Only

NCAM1/CD56 Uni-rAb^TM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

240936A4

Cat no : 98118-1-PBS

Synonyms

Ncam1, CD56, 240936A4, NCAM 1, Ncam

---

Validation Data Gallery

• 

  FC experiment of mouse bone marrow cells using 98118-1-RR (same clone as 98118-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD56 Rabbit Recombinant Antibody (98118-1-RR, Clone: 240936A4) or 0.25 ug Isotype Control, and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98118-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98118-1-RR (same clone as 98118-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD56 Rabbit Recombinant Antibody (98118-1-RR, Clone:240936A4) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98118-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98118-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98118-1-RR against Mouse CD56 were performed. The affinity constant is 9.50 nM.

---

Product Information

The immunogen of 98118-1-PBS is NCAM1/CD56 Fusion Protein expressed in E. coli.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Fusion Protein
• Full Name: neural cell adhesion molecule 1
• Calculated Molecular Weight: 119 kDa
• Gene Symbol: Ncam1
• Gene ID (NCBI): 17967
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Neural cell adhesion molecule 1 (NCAM1, also known as CD56, NCAM, and MSK39) is a membrane-bound cell surface glycoprotein and a member of the immunoglobulin supergene family, which induces cell-to-cell interactions during embryonic development, cell migration, and organogenesis (PMID: 8013635; 1855476; 1391354). Mouse natural killer (NK) cells do not express the murine homolog of CD56 (PMID: 17100875). The molecular weight of NCAM1 changes from the 120 kDa isoform in normal tissue to the 140/180 kDa isoforms in tumors (PMID: 10086383).