CD38 Recombinant antibody

CD38 Uni-rAb^TM Recombinant Antibody for WB, ELISA

Host / Isotype

Mouse / IgG

Reactivity

rabbit

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

241357C3

Cat no : 84689-1-MR

Synonyms

Cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, ADP-ribosyl cyclase 1, ADPRC 1, 2'-phospho-ADP-ribosyl cyclase

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Validation Data Gallery

• 

  WB analysis of rabbit splenocytes using 84689-1-MR

  rabbit splenocytes were subjected to SDS PAGE followed by western blot with 84689-1-MR (CD38 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of rabbit serum using 84689-1-MR

  rabbit serum was subjected to SDS PAGE followed by western blot with 84689-1-MR (CD38 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: rabbit splenocytes cells, rabbit serum

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 84689-1-MR is CD38 Fusion Protein expressed in E. coli.

• Tested Reactivity: rabbit
• Host / Isotype: Mouse / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Fusion Protein
• Full Name: CD38
• Observed Molecular Weight: 45-50 kDa
• Gene Symbol: CD38
• Gene ID (NCBI): 100009409
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).