Product Information
66779-1-PBS targets CD16 in IHC, IF-P, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | CD16 fusion protein Ag9787 Predict reactive species |
Full Name | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
Calculated Molecular Weight | 254 aa, 29 kDa |
GenBank Accession Number | BC017865 |
Gene Symbol | CD16a |
Gene ID (NCBI) | 2214 |
ENSEMBL Gene ID | ENSG00000203747 |
RRID | AB_2918477 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P08637 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B.