CD107a / LAMP1 Polyclonal antibody, PBS Only

CD107a / LAMP1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 21997-1-PBS

Synonyms

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Validation Data Gallery

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  WB analysis using 21997-1-AP (same clone as 21997-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21997-1-AP (CD107a / LAMP1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 21997-1-AP (same clone as 21997-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 21997-1-AP (LAMP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 21997-1-AP (same clone as 21997-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 21997-1-AP (LAMP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 21997-1-AP (same clone as 21997-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 21997-1-AP (LAMP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 21997-1-AP (same clone as 21997-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 21997-1-AP (CD107a / LAMP1 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 21997-1-AP (same clone as 21997-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 21997-1-AP (CD107a / LAMP1 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human gliomas using 21997-1-AP (same clone as 21997-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 21997-1-AP (LAMP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas using 21997-1-AP (same clone as 21997-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 21997-1-AP (LAMP1 antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human pancreas using 21997-1-AP (same clone as 21997-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 21997-1-AP (LAMP1 antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 21997-1-PBS in a different storage buffer formulation.

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Product Information

21997-1-PBS targets CD107a / LAMP1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: CD107a / LAMP1 fusion protein Ag17367
• Full Name: lysosomal-associated membrane protein 1
• Calculated Molecular Weight: 417 aa, 45 kDa
• Observed Molecular Weight: 90-120 kDa
• GenBank Accession Number: BC021288
• Gene Symbol: LAMP1
• Gene ID (NCBI): 3916
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

LAMP1 (also known as CD107a) is a 90-120 kDa heavily glycosylated membrane protein enriched in the lysosomal membrane. LAMP1 functions to provide selectins with carbohydrate ligands. This protein has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells and may also play a role in tumor cell differentiation and metastasis.