- Featured Product
- KD/KO Validated
CBX4 Polyclonal antibody, PBS Only
CBX4 Polyclonal Antibody for WB, IF, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IF, Indirect ELISA
Conjugate
Unconjugated
Cat no : 18544-1-PBS
Synonyms
Validation Data Gallery
Product Information
18544-1-PBS targets CBX4 in WB, IF, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | CBX4 fusion protein Ag13425 |
Full Name | chromobox homolog 4 (Pc class homolog, Drosophila) |
Calculated Molecular Weight | 61 kDa |
Observed Molecular Weight | ~75 kDa |
GenBank Accession Number | BC014967 |
Gene Symbol | CBX4 |
Gene ID (NCBI) | 8535 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
CBX4, also named as E3 SUMO-protein ligase CBX4 or Polycomb 2 homolog, is a 560 amino acid protein, which contains 1 chromo domain. CBX4 facilitates SUMO1 conjugation by UBE2I. CBX4 acting as a transcriptional co-repressor is involved in maintaining the transcriptionally repressive state of genes, modifies chromatin, rendering it heritably changed in its expressibility. CBX4 localizes in the nucleus and is widely expressed in various tissues. The calculated molecular weight of CBX4 is 61 kDa, but the modified CBX4 may be a 70-75 kDa protein.