- Featured Product
- KD/KO Validated
BMPR2 Polyclonal antibody, PBS Only
BMPR2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, IP, Indirect ELISA
Conjugate
Unconjugated
Cat no : 19087-1-PBS
Synonyms
Validation Data Gallery
Product Information
19087-1-PBS targets BMPR2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | BMPR2 fusion protein Ag5868 |
Full Name | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
Calculated Molecular Weight | 115 kDa |
Observed Molecular Weight | 120 kDa |
GenBank Accession Number | BC052985 |
Gene Symbol | BMPR2 |
Gene ID (NCBI) | 659 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
BMPs (bone morphogenetic protein) are involved in endochondral bone formation and embryogenesis. BMPR2 encodes a member of the (BMP) receptor family of transmembrane serine/threonine kinases. It is a widely expressed receptor, with high mRNA expression during development in many tissues. The dimer of BMPR2 receptors (70-80 kD) forms a complex with a dimer of type I BMPR1(50-55 kD) in signal transduction. This antibody recognizes endogenous levels of total BMPR2 protein, including 115 kD precursor, 75 kD mature form, and 150 kD dimer.