ASCC1 Polyclonal antibody, PBS Only

ASCC1 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 12301-1-PBS

Synonyms

SMABF2, CGI18, CGI 18, ASCC 1, ASC1p50

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Validation Data Gallery

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  WB analysis using 12301-1-AP (same clone as 12301-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12301-1-AP (ASCC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12301-1-PBS in a different storage buffer formulation.

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Product Information

12301-1-PBS targets ASCC1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: ASCC1 fusion protein Ag2946
• Full Name: activating signal cointegrator 1 complex subunit 1
• Calculated Molecular Weight: 45.5 kDa
• Observed Molecular Weight: 45.5 kDa
• GenBank Accession Number: BC012291
• Gene Symbol: ASCC1
• Gene ID (NCBI): 51008
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

ASCC1 (also known as p50) is a subunit of an uncharacterized complex, the activating signal co-integrator complex (ASCC). ASCC1 has been reported as regulator fo NF-kB pathway and potently inhibits the expression of NF-kB target genes. Mutations in ASCC1 in patients with Barrett esophagus (BE) have been identified as a risk factor of esophageal adenocarcinoma (EAC).