Anticorps Polyclonal de lapin anti-ZIC1

ZIC1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 25004-1-AP

Synonymes

ZIC, ZIC1, Zinc finger protein ZIC 1, ZNF201

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Galerie de données de validation

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  WB analysis using 25004-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 25004-1-AP (ZIC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  WB analysis of Y79 using 25004-1-AP

  Y79 cells were subjected to SDS PAGE followed by western blot with 25004-1-AP (ZIC1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules ROS1728, cellules PC-12, cellules Y79

Dilution recommandée

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

25004-1-AP cible ZIC1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ZIC1 Protéine recombinante Ag13400
• Nom complet: Zic family member 1 (odd-paired homolog, Drosophila)
• Masse moléculaire calculée: 447 aa, 48 kDa
• Poids moléculaire observé: ~50 kDa
• Numéro d’acquisition GenBank: BC104848
• Symbole du gène: ZIC1
• Identification du gène (NCBI): 7545
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

ZIC1 is a member of the Zinc finger of the cerebellum (ZIC) protein family. In vertebrates, the ZIC gene family plays an important role in neural crest and subsequent cerebellar development. Mutations in ZIC family members have demonstrated that they are essential for proper development of the neural tube, left-right symmetry, and muscle and skeletal development. It has been reported that ZIC1 participates in the regulation of cell proliferation in the dorsal neural tube by inhibition of neural differentiation. Furthermore, ZIC1 is potentially involved in the oncogenesis of undifferentiated nervous system tumors. (PMID:17936758)