Anticorps Polyclonal de lapin anti-UNC5D-Specific

UNC5D-Specific Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications

1

N° de cat : 20241-1-AP

Synonymes

KIAA1777, Netrin receptor UNC5D, PRO34692, Protein unc 5 homolog 4, Protein unc 5 homolog D, unc 5 homolog D (C. elegans), UNC5D, Unc5h4

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Galerie de données de validation

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  WB analysis of mouse kidney using 20241-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 20241-1-AP (UNC5D-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse kidney using 20241-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 20241-1-AP (UNC5D-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu rénal de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

20241-1-AP cible UNC5D-Specific dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: unc-5 homolog D (C. elegans)
• Masse moléculaire calculée: 106 kDa
• Poids moléculaire observé: 59-65 kDa
• Numéro d’acquisition GenBank: NM_080872
• Symbole du gène: UNC5D
• Identification du gène (NCBI): 137970
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5D.

Publications

Species	Application	Title
human		Sci Adv; The FLRT3-UNC5B checkpoint pathway inhibits T cell-based cancer immunotherapies; Authors - Kushal Prajapati