Anticorps Polyclonal de lapin anti-TSLP

TSLP Polyclonal Antibody for IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain et plus (1)

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

Publications

8

Avis (1)

N° de cat : 13778-1-AP

Synonymes

thymic stromal lymphopoietin, TSLP

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Galerie de données de validation

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  IHC staining of human kidney using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 13778-1-AP (TSLP Antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human kidney using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 13778-1-AP (TSLP Antibody) at dilution of 1:200 (under 40x lens).

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  IHC staining of human prostate cancer using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 13778-1-AP (TSLP Antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human prostate cancer using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 13778-1-AP (TSLP Antibody) at dilution of 1:200 (under 40x lens).

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  IHC staining of human lung using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human lung using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human ovary using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human ovary using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human testis using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human testis using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human testis using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human testis using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human spleen using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human spleen using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human spleen using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human spleen using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 40x lens).

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Applications testées

• Résultats positifs en IHC: tissu rénal humain, tissu de cancer de la prostate humain, tissu ovarien humain, tissu pulmonaire humain, tissu splénique humain, tissu testiculaire humain; il est suggéré de démasquer l'antigène avec un tampon de TE buffer pH 9.0; (*) À défaut, 'le démasquage de l'antigène peut être 'effectué avec un tampon citrate pH 6,0.

Dilution recommandée

• Immunohistochimie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• IHC: See 8 publications below

Informations sur le produit

13778-1-AP cible TSLP dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TSLP Protéine recombinante Ag4771
• Nom complet: thymic stromal lymphopoietin
• Masse moléculaire calculée: 15 kDa, 42 kDa
• Numéro d’acquisition GenBank: BC016720
• Symbole du gène: TSLP
• Identification du gène (NCBI): 85480
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain, it mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Another isoform of this protein may act as an antimicrobial peptide in the oral cavity and on the skin (PMID: 24850429).

Publications

Species	Application	Title
human,mouse	IHC	Int Immunopharmacol; Hypoxia induces the production of epithelial-derived cytokines in eosinophilic chronic rhinosinusitis with nasal polyps; Authors - Meiping Zhang
human	IHC	Br J Dermatol; Elevations in Th2-initiating cytokines (IL-33, IL-25, TSLP) in lesional skin from Chronic Spontaneous ("Idiopathic") Urticaria.; Authors - A B Kay
human	IHC	J Immunol Res; Thymic Stromal Lymphopoietin Is Implicated in the Pathogenesis of Bullous Pemphigoid by Dendritic Cells.; Authors - Si-Zhe Li
human,mouse	WB,IHC	J Transl Med; TSLP promoting B cell proliferation and polarizing follicular helper T cell as a therapeutic target in IgG4-related disease; Authors - Hui Lu
human	IHC	Mediators Inflamm; Expression of Thymic Stromal Lymphopoietin in Immune-Related Dermatoses; Authors - Si-Zhe Li
human,mouse	WB,IHC	Int Immunopharmacol; Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes; Authors - Xun Chen

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

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FH

Becky (Verified Customer) (07-30-2018)

It would be great to have this ab stable at 4C. I only use 1uL at a time for ELISA, and storage is -20.

• Applications: Other (please state below),
• Primary Antibody Dilution: 1ug/mL
• Cell Tissue Type: recombinant human TSLP protein coated at 2ug/mL