Anticorps Polyclonal de lapin anti-STRA6
STRA6 Polyclonal Antibody for WB, ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, souris et plus (1)
Applications
WB, IF, IHC, ELISA
Conjugaison
Non conjugué
N° de cat : 22001-1-AP
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en WB | tissu rénal de souris, tissu rénal de rat |
Dilution recommandée
Application | Dilution |
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Western Blot (WB) | WB : 1:1000-1:4000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Applications publiées
WB | See 5 publications below |
IHC | See 1 publications below |
IF | See 3 publications below |
Informations sur le produit
22001-1-AP cible STRA6 dans les applications de WB, IF, IHC, ELISA et montre une réactivité avec des échantillons Humain, souris
Réactivité | Humain, souris |
Réactivité citée | rat, Humain, souris |
Hôte / Isotype | Lapin / IgG |
Clonalité | Polyclonal |
Type | Anticorps |
Immunogène | STRA6 Protéine recombinante Ag17591 |
Nom complet | stimulated by retinoic acid gene 6 homolog (mouse) |
Masse moléculaire calculée | 667 aa, 74 kDa |
Poids moléculaire observé | 73-78 kDa |
Numéro d’acquisition GenBank | BC025256 |
Symbole du gène | STRA6 |
Identification du gène (NCBI) | 64220 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Purification par affinité contre l'antigène |
Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
STRA6, also known as MCOPS9 and PP14296. Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin. (PMID:9452451; 18316031; 22665496; 21368206; 22665496).
Protocole
Product Specific Protocols | |
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WB protocol for STRA6 antibody 22001-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Sci Rep TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins. | ||
Cancers (Basel) ANLN Promotes the Proliferation and Migration of Gallbladder Cancer Cells via STRA6-Mediated Activation of PI3K/AKT Signaling | ||
Endocrinology De novo-synthesized retinoic acid in ovarian antral follicles enhances FSH-mediated ovarian follicular cell differentiation and female fertility. | ||
Lab Invest Nuclear receptor binding factor 2 (NRBF2) is required for learning and memory. | ||
eNeuro Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment. |
Avis
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
FH Christian (Verified Customer) (02-19-2020) | The antibody works quite well, not many unspecific bands.
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