Anticorps Polyclonal de lapin anti-SLC36A4

SLC36A4 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 24066-1-AP

Synonymes

PAT4, SLC36A4

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Galerie de données de validation

• 

  WB analysis of A549 using 24066-1-AP

  A549 cells were subjected to SDS PAGE followed by western blot with 24066-1-AP (SLC36A4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HEK-293 using 24066-1-AP

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 24066-1-AP (SLC36A4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of PC-3 using 24066-1-AP

  PC-3 cells were subjected to SDS PAGE followed by western blot with 24066-1-AP (SLC36A4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules A549, cellules HEK-293, cellules PC-3

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

24066-1-AP cible SLC36A4 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC36A4 Protéine recombinante Ag21142
• Nom complet: solute carrier family 36 (proton/amino acid symporter), member 4
• Masse moléculaire calculée: 504 aa, 56 kDa
• Poids moléculaire observé: 41-66 kDa
• Numéro d’acquisition GenBank: BC047374
• Symbole du gène: SLC36A4
• Identification du gène (NCBI): 120103
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

SLC36A4 (also known as proton-coupled amino-acid transporter 4, PAT4), is a member of the solute carrier (SLC) 36 family which functions as transporter for amino acids and derivatives. SLC36A4 is widely distributed at the mRNA level in normal tissues and many cancer cell lines. It modulates the mTORC1 signaling and is essential for the proliferation of cancer cells. In addition, small GTPase Rab12 controls the degradation of SLC36A4, which indirectly modulates mTORC1 activity and autophagy. This antibody can recognize the endogenous SLC36A4 protein in multiple cell lines.