Anticorps Polyclonal de lapin anti-SLC25A39

SLC25A39 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF, ELISA

Conjugaison

Non conjugué

Publications

6

Avis (1)

N° de cat : 14963-1-AP

Synonymes

CGI 69, CGI69, PRO2163, SLC25A39

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Galerie de données de validation

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  WB analysis using 14963-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 14963-1-AP (SLC25A39 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse brain using 14963-1-AP

  mouse brain tissue was subjected to SDS PAGE followed by western blot with 14963-1-AP (SLC25A39 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu cérébral de souris, tissu cérébral de rat

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 6 publications below
• IF: See 1 publications below

Informations sur le produit

14963-1-AP cible SLC25A39 dans les applications de WB, IF, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC25A39 Protéine recombinante Ag6825
• Nom complet: solute carrier family 25, member 39
• Masse moléculaire calculée: 39 kDa
• Poids moléculaire observé: 37-39 kDa
• Numéro d’acquisition GenBank: BC001398
• Symbole du gène: SLC25A39
• Identification du gène (NCBI): 51629
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

SLC25A39, a member of the mitochondrial carrier family, is a mitochondrial transporter for basic amino acids localized to mitochondria. SLC25A39 can be expressed in human testis, kidney, heart, brain, liver and spleen. It has been reported that SLC25A39 is essential for heme biosynthesis in mammals. SLC25A29 is associated with mitochondrial protein synthesis and amino acid degradation. (PMID: 19656490, 11139402, 24652292)

Publications

Species	Application	Title
human	WB,IF	Nature; SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells.; Authors - Ying Wang ; KO Validated
human	WB	Nat Commun; Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS.; Authors - Xiaojian Shi
human	WB	Science; Autoregulatory control of mitochondrial glutathione homeostasis; Authors - Yuyang Liu
human	WB	Mol Cell; Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis; Authors - Xiaojian Shi
mouse	WB	Redox Biol; S-Adenosyl-l-methionine restores brain mitochondrial membrane fluidity and GSH content improving Niemann-Pick type C disease; Authors - Leire Goicoechea
mouse	WB	Biol Trace Elem Res; Chronic Exposure to Arsenic and Fluoride Starting at Gestation Alters Liver Mitochondrial Protein Expression and Induces Early Onset of Liver Fibrosis in Male Mouse Offspring; Authors - Wendy L González-Alfonso

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

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FH

Ashish (Verified Customer) (12-18-2023)

n/a

• Applications: Western Blot
• Primary Antibody Dilution: 1:1000
• Cell Tissue Type: EWING SARCOMA CELL LINE