Anticorps Polyclonal de lapin anti-SLC16A2

SLC16A2 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications

6

N° de cat : 20676-1-AP

Synonymes

AHDS, DXS128, DXS128E, MCT 7, MCT 8, MCT7, MCT8, Monocarboxylate transporter 7, Monocarboxylate transporter 8, MRX22, SLC16A2, XPCT

---

Galerie de données de validation

• 

  WB analysis of mouse kidney using 20676-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 20676-1-AP (SLC16A2 Antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse heart using 20676-1-AP

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 20676-1-AP (SLC16A2 Antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse heart using 20676-1-AP

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 20676-1-AP (SLC16A2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of L02 using 20676-1-AP

  L02 cells were subjected to SDS PAGE followed by western blot with 20676-1-AP (SLC16A2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

---

Applications testées

• Résultats positifs en WB: tissu rénal de souris, cellules L02, tissu cardiaque de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 6 publications below

Informations sur le produit

20676-1-AP cible SLC16A2 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
• Masse moléculaire calculée: 60 kDa
• Poids moléculaire observé: 50-65 kDa
• Numéro d’acquisition GenBank: NM_006517
• Symbole du gène: SLC16A2
• Identification du gène (NCBI): 6567
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

SLC16A2, also named as MCT8 and XPCT, belongs to the major facilitator superfamily and Monocarboxylate porter (TC 2.A.1.13) family. SLC16A2 is a very active and specific thyroid hormone transporter. SLC16A2 stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. It does not transport Leu, Phe, Trp or Tyr. Defects in SLC16A2 are the cause of monocarboxylate transporter 8 deficiency (MCT8 deficiency). This antibody is specific to SLC16A2.

Publications

Species	Application	Title
mouse	WB	Int J Mol Sci; Smoothelin-Like Protein 1 Regulates the Thyroid Hormone-Induced Homeostasis and Remodeling of C2C12 Cells via the Modulation of Myosin Phosphatase.; Authors - Evelin Major
human	WB	Front Pharmacol; Hydrogen Sulfide Promotes Thyroid Hormone Synthesis and Secretion by Upregulating Sirtuin-1.; Authors - Xue Zhao
mouse	WB	PLoS One; Tissue-Specific Expression of Monocarboxylate Transporters during Fasting in Mice.; Authors - Alexandra Schutkowski
rat	WB	Pharm Res; Participation of Monocarboxylate Transporter 8, But Not P-Glycoprotein, in Carrier-Mediated Cerebral Elimination of Phenytoin across the Blood-Brain Barrier.; Authors - Ryuta Jomura
human	WB	Toxicology; MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity; Authors - Min Liu
human	WB	Toxicology; BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity; Authors - Min Liu