Anticorps Polyclonal de lapin anti-SCRN1

SCRN1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, CoIP, ELISA

Conjugaison

Non conjugué

Publications

3

N° de cat : 14303-1-AP

Synonymes

KIAA0193, SCRN1, secernin 1, SES1

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Galerie de données de validation

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  WB analysis of A549 using 14303-1-AP

  A549 cells were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of A549 using 14303-1-AP

  A549 cells were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse brain using 14303-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HeLa using 14303-1-AP

  HeLa cells were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse brain using 14303-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 14303-1-AP (SCRN1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules A549, cellules HeLa, tissu cérébral de souris

Dilution recommandée

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• CoIP: See 1 publications below

Informations sur le produit

14303-1-AP cible SCRN1 dans les applications de WB, CoIP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SCRN1 Protéine recombinante Ag5413
• Nom complet: secernin 1
• Masse moléculaire calculée: 46 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC040492
• Symbole du gène: SCRN1
• Identification du gène (NCBI): 9805
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

SCRN genes encode protein members of the secernin family including Secernin 1, Secernin 2 and Secernin 3. Function of Secernin 2 and Secernin 3 are so far not well understood. Secernin 1 is a novel 50-kDa cytosolic protein that appears to be involved in the regulation of exocytosis from peritoneal mast cells. Secernin-1 a novel tumor-associated antigen (TAA) and may be a universal marker of different cancer types including gastric cancer, which has been validated by several researches. Measurement of SCRN1 can be used in the early detection of cancer or in the surveillance of patients who undergo surgery.

Publications

Species	Application	Title
mouse	WB	Front Mol Neurosci; Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice; Authors - Xiaoxia Li
mouse	WB	Biochem Biophys Res Commun; Proteomic profiling of brain cortex tissues in a Tau transgenic mouse model of Alzheimer's disease.; Authors - Seong-Hun Chang
human	CoIP	J Mol Cell Biol; ARTC1-mediated VAPB ADP-ribosylation regulates calcium homeostasis; Authors - Xueyao Ma