Anticorps Polyclonal de lapin anti-RORC

RORC Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris et plus (2)

Applications

WB, IF, IHC, ChIP, ELISA

Conjugaison

Non conjugué

N° de cat : 13205-1-AP

Synonymes

NR1F3, Nuclear receptor ROR gamma, Nuclear receptor RZR gamma, Nuclear receptor RZR-gamma, RAR related orphan receptor C, ROR gamma T, RORC, RORG, RORyT, RORγt, RZR GAMMA, RZRG, TOR



Applications testées

Résultats positifs en WBcellules HEK-293, cellules Jurkat

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

13205-1-AP cible RORC dans les applications de WB, IF, IHC, ChIP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Réactivité citéerat, Humain, porc, poulet, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène RORC Protéine recombinante Ag3961
Nom complet RAR-related orphan receptor C
Masse moléculaire calculée 518 aa, 58 kDa
Poids moléculaire observé 58 kDa
Numéro d’acquisition GenBankBC031554
Symbole du gène RORC
Identification du gène (NCBI) 6097
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The Nuclear receptors retinoic acid receptor-related orphan receptor gamma (RORγ or RORc, also known as NR1F3) was the third and most recent ROR group member to be discovered, following the prior disclosures of RORα (RORa or NR1F1) and RORβ (RORb or NR1F2) (PMID:24502334). Studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.RORC has 2 isoforms with the MW of 56 kDa and 58 kDa.

Protocole

Product Specific Protocols
WB protocol for RORC antibody 13205-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,ChIP

Oncogene

Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc

Authors - Ying-Nan Wang
ratIF

Headache

Aryl hydrocarbon receptors improve migraine-like pain behaviors in rats through the regulation of regulatory T cell/T-helper 17 cell-related homeostasis

Authors - Liu Yang
humanIHC

Front Oncol

Analysis of the potential association between ferroptosis and immune in hepatocellular carcinoma and their relationship with prognosis

Authors - Kai Wen
ratWB

Biomed Pharmacother

Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.

Authors - Yu Xia
ratWB

Phytomedicine

Extracts of Poria cocos improve functional dyspepsia via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa

Authors - Yijun Tu
mouseWB

Food Funct

Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.

Authors - Huichao Zhao

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Priya (Verified Customer) (06-21-2023)

Used this antibody for Caco2 cells andmice tissue

  • Applications: Western Blot
  • Primary Antibody Dilution: 1 to 1000
  • Cell Tissue Type: Caco2, Mice colon