Anticorps Recombinant de lapin anti-RC3H1

RC3H1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241046G10

N° de cat : 84323-1-PBS

Synonymes

241046G10, KIAA2025, RING finger protein 198, RNF198, ROQUIN

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Galerie de données de validation

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  WB analysis using 84323-1-RR (same clone as 84323-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84323-1-RR (RC3H1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84323-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84323-1-PBS cible RC3H1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: ring finger and CCCH-type zinc finger domains 1
• Poids moléculaire observé: 130-140 kDa
• Numéro d’acquisition GenBank: NM_172071
• Symbole du gène: RC3H1
• Identification du gène (NCBI): 149041
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Roquin-1 (Rc3h1) is an E3 ubiquitin ligase originally discovered in a mutational screen for genetic factors contributory to systemic lupus erythematosus-like symptoms in mice. A single base pair mutation in the Rc3h1 gene resulted in the manifestation of autoantibody production and sustained immunological inflammation characterized by excessive T follicular helper cell activation and formation of germinal centers. (PMID: 26673963)

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