Anticorps Polyclonal de lapin anti-PI3 Kinase p55 Gamma

PI3 Kinase p55 Gamma Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications

6

N° de cat : 55036-1-AP

Synonymes

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Galerie de données de validation

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Applications testées

Dilution recommandée

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 6 publications below

Informations sur le produit

55036-1-AP cible PI3 Kinase p55 Gamma dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
• Masse moléculaire calculée: 54 kDa
• Numéro d’acquisition GenBank: NM_003629
• Symbole du gène: PIK3R3
• Identification du gène (NCBI): 8503
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

PIK3R3, also named as p55PIK, belongs to the PI3K p85 subunit family. It binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During INS stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The antibody is specific to PIK3R3.

Publications

Species	Application	Title
mouse	WB	RNA Biol; MicroRNA-432 targeting E2F3 and P55PIK inhibits myogenesis through PI3K/AKT/mTOR signaling pathway.; Authors - Meilin Ma
human	WB	Mol Biol Cell; MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway.; Authors - Xu Lin L
human	WB	Tumour Biol; MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3.; Authors - Gang Cao
rat	WB	Transl Androl Urol; Study on the mechanism of aging-related erectile dysfunction based on bioinformatics and experimental verification; Authors - Taotao Sun
human	WB	Tumour Biol; Upregulation of HOXB7 promotes the tumorigenesis and progression of gastric cancer and correlates with clinical characteristics.; Authors - Jia-Qin Cai
rat	WB	Andrology; Saxagliptin alleviates erectile dysfunction through increasing SDF-1 in diabetes mellitus; Authors - Taotao Sun