Anticorps Monoclonal anti-TrkA

TrkA Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3B11C7

N° de cat : 60548-1-PBS

Synonymes

NTRK1, Trk A, TRK, p140 TrkA, MTC

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Galerie de données de validation

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  WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

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  WB analysis of NK-92 using 60548-1-Ig (same clone as 60548-1-PBS)

  NK-92 cells were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 60548-1-Ig (same clone as 60548-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60548-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60548-1-PBS cible TrkA dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TrkA Protéine recombinante Ag27985
• Nom complet: neurotrophic tyrosine kinase, receptor, type 1
• Masse moléculaire calculée: 88 kDa
• Poids moléculaire observé: 140 kDa
• Numéro d’acquisition GenBank: NM_001007792
• Symbole du gène: NTRK1
• Identification du gène (NCBI): 4914
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).

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