• Phare
  • Validé par KD/KO

Anticorps Polyclonal de lapin anti-Marcksl1

Marcksl1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF, IHC, ELISA

Conjugaison

Non conjugué

N° de cat : 10002-2-AP

Synonymes

AL022768, AW215397, AW536807, D4Bc1, F52, MacMARCKS, Macs 2, Macs 3, Macs2, Macs3, MARCKS like 1, Marcksl1, Mlp, Mrp



Applications testées

Résultats positifs en WBtissu cérébral de souris

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

10002-2-AP cible Marcksl1 dans les applications de WB, IF, IHC, ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Réactivité citéeHumain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Protéine recombinante
Nom complet MARCKS-like 1
Masse moléculaire calculée 40 kDa
Poids moléculaire observé 60 kDa
Numéro d’acquisition GenBankBC006757
Symbole du gène Marcksl1
Identification du gène (NCBI) 17357
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

MacMARCKS is a member of MARCKS family of PKC substrate. It is widely used in the signal transduction studies as an indictor of PKC activation. The protein has a calculated molecular weight of 20 kDa and an apparent molecular weight of 42-45 kDa in different species on SDS PAGE. MacMARCKS functions in many aspects of cell physiology including integrin activation, cell spreading and phagocytosis. Its functions are though to associate with its ability in binding and regulating actin and microtubule cytoskeleton. Current evidence indicated that this protein also involved controls membrane fluidity and molecular mobility of membrane proteins

Protocole

Product Specific Protocols
WB protocol for Marcksl1 antibody 10002-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIHC

J Exp Med

Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signaling.

Authors - Takashi Kanaya
humanWB,IHC

J Biol Chem

The long noncoding RNA lncZic2 drives the self-renewal of liver tumor-initiating cells via the protein kinase C substrates MARCKS and MARCKSL1.

Authors - Zhenzhen Chen
  • KO Validated
human,mouseWB,IHC

Mol Cell Biol

c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells.

Authors - Bj?rkblom Benny B
  • KD Validated
mouseWB

PLoS One

Colonic miRNA Expression/Secretion, Regulated by Intestinal Epithelial PepT1, Plays an Important Role in Cell-to-Cell Communication during Colitis.

Authors - Saravanan Ayyadurai
humanWB,IF

Exp Cell Res

The regulation of MacMARCKS expression by integrin beta3.

Authors - van den Bout Iman I
humanIHC

Clin Exp Metastasis

Identification of estrogen-responsive genes involved in breast cancer metastases to the bone.

Authors - Wang Jun J