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Anticorps Polyclonal de lapin anti-L-Myc

L-Myc Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 14584-1-AP

Synonymes

bHLHe38, LMYC, L-Myc, MYCL, MYCL1, Protein L Myc 1

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using L-Myc Polyclonal antibody (14584-1-AP)

    WB analysis using 14584-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 14584-1-AP (L-Myc antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Applications testées

Résultats positifs en WBcellules NCI-H1299, U266 cells

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

WBSee 1 publications below

Informations sur le produit

14584-1-AP cible L-Myc dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Réactivité citéeHumain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène L-Myc Protéine recombinante Ag6105
Nom complet v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
Masse moléculaire calculée 40 kDa
Poids moléculaire observé68 kDa
Numéro d’acquisition GenBankBC011864
Symbole du gène MYCL1
Identification du gène (NCBI) 4610
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

The MYC gene family consists of 3 members, C-MYC, L-MYC, and N-MYC, all of which belong to the superfamily of basic helix-loop-helix leucine zipper (bHLHLZ) DNA binding proteins. L-MYC encodes a nuclear phosphoprotein with 364 amino acids, heterodimerizing with partner protein Max and acts as a transcription factor to control the expression of target genes. L-Myc is involved in many biological processes, including cell proliferation, differentiation, apoptosis and has been found to be amplified and over-expressed in some malignancies. L-Myc amplification has been reported in small-cell lung cancer (PMID: 25528583, 33524794). The observed molecular weight of L-Myc is 68 kDa, which is consistent with the description in the literature (PMID: 8657155).

Protocole

Product Specific Protocols
WB protocol for L-Myc antibody 14584-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Nat Cell Biol

Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis.

Authors - Donglim Esther Park
View Article

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

FH

Sarah (Verified Customer) (10-27-2023)

Antibody worked well for western blot

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:1000