Anticorps Polyclonal de lapin anti-M-CSF
M-CSF Polyclonal Antibody for ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain et plus (1)
Applications
WB, IF, ELISA, Cell treatment
Conjugaison
Non conjugué
N° de cat : 14779-1-AP
Synonymes
Galerie de données de validation
Applications testées
Applications publiées
WB | See 8 publications below |
IF | See 1 publications below |
Informations sur le produit
14779-1-AP cible M-CSF dans les applications de WB, IF, ELISA, Cell treatment et montre une réactivité avec des échantillons Humain
Réactivité | Humain |
Réactivité citée | Humain, souris |
Hôte / Isotype | Lapin / IgG |
Clonalité | Polyclonal |
Type | Anticorps |
Immunogène | M-CSF Protéine recombinante Ag6294 |
Nom complet | colony stimulating factor 1 (macrophage) |
Masse moléculaire calculée | 60 kDa |
Poids moléculaire observé | 70 kDa |
Numéro d’acquisition GenBank | BC021117 |
Symbole du gène | M-CSF |
Identification du gène (NCBI) | 1435 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Purification par affinité contre l'antigène |
Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
Colony stimulating factor-1 (CSF-1) is a homodimeric glycoprotein that humorally regulates the proliferation and differentiation of mononuclear phagocytic cells and locally regulates cells of the female reproductive tract. Alternative splicing of the human CSF-1 mRNA leads to alternative expression of the CSF-1 homodimer as a secreted glycoprotein or as a membrane-spanning molecule with cell surface biological activity. CSF-1 is predominantly secreted as highly sulfated species of 375- and 250-kDa with a smaller amount of a 100-kDa species. The three predominant CSF-1 species were shown to be an 80-kDa homodimer, an 80-kDa/50-kDa heterodimer, and a 50-kDa homodimer. (PMID: 1733926) This antibody could recognieze 60 kDa, 48 kDa, 29 kDa isoforms.
Publications
Species | Application | Title |
---|---|---|
J Control Release Chemoattractants driven and microglia based biomimetic nanoparticle treating TMZ-resistant glioblastoma multiforme. | ||
J Nanobiotechnology Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM. | ||
Biomed Pharmacother Anti-osteoporotic effects of alisol C 23-acetate via osteoclastogenesis inhibition. | ||
Int J Biol Sci Macrophage Colony-stimulating Factor Mediates the Recruitment of Macrophages in Triple negative Breast Cancer. | ||
Invest Ophthalmol Vis Sci CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization. | ||
Front Physiol Heat Stress Modulates a Placental Immune Response Associated With Alterations in the Development of the Fetal Intestine and Its Innate Immune System in Late Pregnant Mouse. |