Anticorps Polyclonal de lapin anti-LNX1

LNX1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 13124-1-AP

Synonymes

ligand of numb protein X 1, LNX, LNX1, MPDZ, Numb binding protein 1, PDZRN2

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Galerie de données de validation

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  WB analysis of mouse testis using 13124-1-AP

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 13124-1-AP (LNX1 antibody) at dilution of 1:70 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse kidney using 13124-1-AP

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 13124-1-AP (LNX1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu testiculaire de souris, tissu rénal de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2400

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

13124-1-AP cible LNX1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LNX1 Protéine recombinante Ag3823
• Nom complet: ligand of numb-protein X 1
• Masse moléculaire calculée: 728 aa, 81 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC022983
• Symbole du gène: LNX1
• Identification du gène (NCBI): 84708
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

LNX1 (Ligand of Numb, protein X 1) was originally identified as a binding partner of the cell-fate determinant Numb and was reported to be involved in ubiquitylation and degradation of Numb. LNX1 contains four PDZ domains and may function as a scaffold for a multi-protein complex. LNX1 has two splicing variants, LNX1p70 and LNX1p80. LNX1p70 has the N-terminal Numb binding region and four PDZ domains, whereas LNX1p80 has an additional RING-finger domain at the N-terminus followed by a Numb-binding region and four PDZ domains. This antibody can detect both LNX1p70 and LNX1p80, around 70-80 kDa and 80-100 kDa, respectively.

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