Anticorps Polyclonal de lapin anti-LHX6

• Phare
• Validé par KD/KO

LHX6 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications

2

Avis (1)

N° de cat : 21516-1-AP

Synonymes

LHX6, LHX6.1, LIM homeobox 6, LIM homeobox protein 6, LIM/homeobox protein Lhx6, LIM/homeobox protein Lhx6.1

---

Galerie de données de validation

• 

  WB analysis of HepG2 using 21516-1-AP

  HepG2 cells were subjected to SDS PAGE followed by western blot with 21516-1-AP (LHX6 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

---

Applications testées

• Résultats positifs en WB: cellules HepG2

Dilution recommandée

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 2 publications below

Informations sur le produit

21516-1-AP cible LHX6 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: LHX6 Protéine recombinante Ag16047
• Nom complet: LIM homeobox 6
• Masse moléculaire calculée: 392 aa, 43 kDa
• Poids moléculaire observé: 50-60 kDa
• Numéro d’acquisition GenBank: BC103937
• Symbole du gène: LHX6
• Identification du gène (NCBI): 26468
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

LHX6 is a LIM homeodomain protein similar in structure to ISL-1. LHX6, like ISL-1, contains tandem LIM domains and a homeodomain that regulate its activity both in cis and through interaction with cell-specific factors. LHX6 is highly expressed in the neural crest-derived mesenchyme throughout odontogenesis and down-regulated after birth. However, LHX6 is also expressed in the palate epithelium, oral epithelium, and dental epithelium during craniofacial development. LHX6 regulates migration and specification of neuron subtypes and marks specific neurons. The molecular weight of Endogenous LHX6 is 40 kDa, but the LHX6
PITX2 protein complex is 56 kDa (PMID: 23229549).

Publications

Species	Application	Title
human	WB	Mol Ther Nucleic Acids; Placental trophoblast cell-derived exosomal microRNA-1290 promotes the interaction between endometrium and embryo by targeting LHX6.; Authors - Shuang Shi ; KD Validated
human	WB	Exp Cell Res; Hypoxia-induced exosomes promote hepatocellular carcinoma proliferation and metastasis via miR-1273f transfer.; Authors - You Yu

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.

---

FH

Reyes (Verified Customer) (07-29-2024)

LHX6 (in green) appears to work nicely marking some of my neurons (in red) in human brain FFPE tissue.

• Applications: Immunofluorescence
• Primary Antibody Dilution: 1:100
• Cell Tissue Type: Human Brain Cortex

LHX6 Antibody Immunofluorescence validation (1:100 dilution) in Human Brain Cortex (Cat no:21516-1-AP)