Anticorps Polyclonal de lapin anti-ITLN1/2

ITLN1/2 Polyclonal Antibody for WB, IP, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, IF, FC, IHC, ELISA

Conjugaison

Non conjugué

N° de cat : 11770-1-AP

Synonymes

Endothelial lectin HL 1, Galactofuranose binding lectin, hIntL, HL 1, HL1, Intelectin 1, INTL, ITLN, ITLN 1, ITLN1, ITLN2, LFR, omentin



Applications testées

Résultats positifs en WBtissu de côlon de souris,
Résultats positifs en IPtissu d'appendice de souris

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
Immunoprécipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

11770-1-AP cible ITLN1/2 dans les applications de WB, IP, IF, FC, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Réactivité citéeHumain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène ITLN1/2 Protéine recombinante Ag2424
Nom complet intelectin 1 (galactofuranose binding)
Masse moléculaire calculée 313 aa, 35 kDa
Poids moléculaire observé 35-40 kDa
Numéro d’acquisition GenBankBC020664
Symbole du gène ITLN1
Identification du gène (NCBI) 55600
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

ITLN1, also named as Intelectin 1, has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 is a glycoprotein made up of three 40 kDa subunits cross-linked by disulfide bonds making up a 120-kDa homo-trimer of 295 amino acids and N-linked oligosaccharides (PMID: 17621593). It may play a role in the defense system against microorganisms. Human intelectin-1 is expressed in intestinal goblet cells, and is present at about 200 ng/mL in serum. Intelectin-1 was also shown to be expressed in human endothelial cells and adipocytes of human abdominal adipose tissue. (PMID: 22768319,PMID: 28640441)

Protocole

Product Specific Protocols
WB protocol for ITLN1/2 antibody 11770-1-APDownload protocol
IP protocol for ITLN1/2 antibody 11770-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
IF

Nat Commun

Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates.

Authors - Hye Young Kim
humanIHC, IF

J Exp Med

Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine.

Authors - Yalong Wang
mouseWB,IHC

Mucosal Immunol

Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis.

Authors - L Yi
mouseWB,IF

Front Cell Dev Biol

Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells.

Authors - Xiaochen Niu
humanWB

Fish Shellfish Immunol

Molecular properties and ligand specificity of zebrafish intelectin-2.

Authors - Nongnuch Singrang
humanWB

J Biol Chem

Structures of Xenopus embryonic epidermal lectin reveal a conserved mechanism of microbial glycan recognition.

Authors - Kittikhun Wangkanont