Anticorps Polyclonal de lapin anti-ITLN1/2
ITLN1/2 Polyclonal Antibody for WB, IP, ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, rat, souris
Applications
WB, IP, IF, FC, IHC, ELISA
Conjugaison
Non conjugué
N° de cat : 11770-1-AP
Synonymes
Galerie de données de validation
Applications testées
Résultats positifs en WB | tissu de côlon de souris, |
Résultats positifs en IP | tissu d'appendice de souris |
Dilution recommandée
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:3000 |
Immunoprécipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Applications publiées
WB | See 11 publications below |
IHC | See 4 publications below |
IF | See 6 publications below |
FC | See 1 publications below |
Informations sur le produit
11770-1-AP cible ITLN1/2 dans les applications de WB, IP, IF, FC, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris
Réactivité | Humain, rat, souris |
Réactivité citée | Humain, souris |
Hôte / Isotype | Lapin / IgG |
Clonalité | Polyclonal |
Type | Anticorps |
Immunogène | ITLN1/2 Protéine recombinante Ag2424 |
Nom complet | intelectin 1 (galactofuranose binding) |
Masse moléculaire calculée | 313 aa, 35 kDa |
Poids moléculaire observé | 35-40 kDa |
Numéro d’acquisition GenBank | BC020664 |
Symbole du gène | ITLN1 |
Identification du gène (NCBI) | 55600 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Purification par affinité contre l'antigène |
Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
ITLN1, also named as Intelectin 1, has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 is a glycoprotein made up of three 40 kDa subunits cross-linked by disulfide bonds making up a 120-kDa homo-trimer of 295 amino acids and N-linked oligosaccharides (PMID: 17621593). It may play a role in the defense system against microorganisms. Human intelectin-1 is expressed in intestinal goblet cells, and is present at about 200 ng/mL in serum. Intelectin-1 was also shown to be expressed in human endothelial cells and adipocytes of human abdominal adipose tissue. (PMID: 22768319,PMID: 28640441)
Protocole
Product Specific Protocols | |
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WB protocol for ITLN1/2 antibody 11770-1-AP | Download protocol |
IP protocol for ITLN1/2 antibody 11770-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
Nat Commun Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates. | ||
J Exp Med Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine. | ||
Mucosal Immunol Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis. | ||
Front Cell Dev Biol Neuroprotective Effects of Omentin-1 Against Cerebral Hypoxia/Reoxygenation Injury via Activating GAS6/Axl Signaling Pathway in Neuroblastoma Cells. | ||
Fish Shellfish Immunol Molecular properties and ligand specificity of zebrafish intelectin-2. | ||
J Biol Chem Structures of Xenopus embryonic epidermal lectin reveal a conserved mechanism of microbial glycan recognition. |