Anticorps Polyclonal de lapin anti-FIZ1

FIZ1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 23257-1-AP

Synonymes

FIZ1

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Galerie de données de validation

• 

  WB analysis of Jurkat using 23257-1-AP

  Jurkat cells were subjected to SDS PAGE followed by western blot with 23257-1-AP (FIZ1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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  WB analysis of NIH/3T3 using 23257-1-AP

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 23257-1-AP (FIZ1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

• 

  WB analysis of HEK-293 using 23257-1-AP

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 23257-1-AP (FIZ1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules Jurkat, cellules HEK-293, cellules NIH/3T3

Dilution recommandée

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

23257-1-AP cible FIZ1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: FIZ1 Protéine recombinante Ag19760
• Nom complet: FLT3-interacting zinc finger 1
• Masse moléculaire calculée: 496 aa, 52 kDa
• Poids moléculaire observé: 52 kDa
• Numéro d’acquisition GenBank: BC136512
• Symbole du gène: FIZ1
• Identification du gène (NCBI): 84922
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

FLT3 interacting zinc finger 1 (FIZ1) is a ubiquitous expressed protein that composes of 11 C2H2 zinc finger domains spread over the entire protein in clusters of two, three, or four fingers. The interaction of FIZ1 was mapped to the catalytic domain of FLT3, which is a receptor tyrosine kinase involved in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors (10409713). In the mammalian retina, FIZ1 interacts with NRL (Neural-Retina Leucine-zipper), an essential transcriptional activator of rod photoreceptor-specific genes, and the concentration of FIZ1 in the retina will increase during photoreceptor terminal maturation (18854042).