Anticorps Polyclonal de lapin anti-EGFL7

• Phare
• Validé par KD/KO

EGFL7 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat et plus (1)

Applications

WB, IHC, IF, ELISA

Conjugaison

Non conjugué

Publications(12)

N° de cat : 19291-1-AP

Synonymes

Multiple EGF-like domains protein 7, MEGF7, Epidermal growth factor-like protein 7, EGF-like protein 7, EGF like protein 7

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Galerie de données de validation

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  WB analysis using 19291-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 19291-1-AP (EGFL7 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu oculaire de rat,

Dilution recommandée

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 2 publications below
• WB: See 11 publications below
• IHC: See 4 publications below
• IF: See 1 publications below

Informations sur le produit

19291-1-AP cible EGFL7 dans les applications de WB, IHC, IF, ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Réactivité citée: rat, Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: EGFL7 Protéine recombinante Ag6559
• Nom complet: EGF-like-domain, multiple 7
• Masse moléculaire calculée: 273 aa, 30 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC012377
• Symbole du gène: EGFL7
• Identification du gène (NCBI): 51162
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Epidermal growth factor-like domain-containing protein 7 (EGFL7), also known as vascular endothelial statin, is an endothelial cell-derived secreted factor that regulates vascular tube formation. This protein may be involved in the growth and proliferation of tumor cells. Recent studies have reported elevated expression of EGFL7 in several tumors and cancer cell lines, including kidney tumors, malignant gliomas, hepatocellular carcinomas, and colon cancers.

Publications

Species	Application	Title
human	WB	Blood Adv; The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models.; Authors - Yousef Salama ; KD Validated
human	WB	Mol Ther Nucleic Acids; Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay.; Authors - Chunqing Yang
human	WB,IHC,IF	Front Oncol; Novel Expression of EGFL7 in Osteosarcoma and Sensitivity to Cisplatin.; Authors - Qing Liu
mouse,rat	WB	Sci China Life Sci; Role of EGFL7/EGFR-signaling pathway in migration and invasion of growth hormone-producing pituitary adenomas.; Authors - Qian Liu
human	WB	Hum Gene Ther; Attenuation of EGFL7 expression inhibits growth hormone-producing pituitary adenomas growth and invasion.; Authors - Qian Liu
human	WB,IHC	Tumour Biol; EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway.; Authors - Jianpeng Wang

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