Anticorps Polyclonal de lapin anti-DPP3

• Phare
• Validé par KD/KO

DPP3 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications

3

N° de cat : 10650-1-AP

Synonymes

Dipeptidyl aminopeptidase III, Dipeptidyl arylamidase III, dipeptidyl peptidase 3, Dipeptidyl peptidase III, DPP III, DPP3, DPPIII

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Galerie de données de validation

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  WB analysis of mouse thymus using 10650-1-AP

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 10650-1-AP (DPP3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse thymus using 10650-1-AP

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 10650-1-AP (DPP3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of human placenta using 10650-1-AP

  human placenta tissue were subjected to SDS PAGE followed by western blot with 10650-1-AP (DPP3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse thymus using 10650-1-AP

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 10650-1-AP (DPP3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu de thymus de souris, tissu placentaire humain

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 3 publications below

Informations sur le produit

10650-1-AP cible DPP3 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DPP3 Protéine recombinante Ag1022
• Nom complet: dipeptidyl-peptidase 3
• Masse moléculaire calculée: 83 kDa
• Poids moléculaire observé: 69 kDa, 83 kDa
• Numéro d’acquisition GenBank: BC007221
• Symbole du gène: DPP3
• Identification du gène (NCBI): 10072
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

DPP3 (dipeptidyl-peptidase 3), also known as DPPIII, is one of the dipeptidyl aminopeptidases, that belongs to the peptidase M49 family. DPP3 is a metalloenzyme containing one Zn2+ ion in its active site. Furthermore, It was shown to have a novel zinc-binding motif ( HELLGH). DPP3 has been reported as an important enkephalin-degrading enzyme in the central nervous system, in human neutrophils.It has 3 isoforms produced by alternative splicing. Increased activity of DPP3 is associated with endometrial and ovarian cancers.

Publications

Species	Application	Title
mouse	WB	J Biol Chem; Dipeptidyl peptidase 3 modulates the renin-angiotensin system in mice.; Authors - Shalinee Jha ; KO Validated
mouse	WB	Environ Mol Mutagen; Proteomic biomarkers for prenatal bisphenol A-exposure in mouse immune organs.; Authors - Yang Mihi M
mouse	WB	Int Immunopharmacol; Dipeptidyl peptidase 3 is essential for maintaining osteoblastic differentiation under a high-glucose environment by inhibiting apoptosis, oxidative stress and inflammation through the modulation of the Keap1-Nrf2 pathway; Authors - Xiaofeng Li