Anticorps Polyclonal de lapin anti-DPEP1

• Phare
• Validé par KD/KO

DPEP1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris et plus (1)

Applications

WB, FC, IHC, ELISA

Conjugaison

Non conjugué

Publications

6

N° de cat : 12222-1-AP

Synonymes

Dehydropeptidase I, Dipeptidase 1, dipeptidase 1 (renal), DPEP1, hRDP, MBD1, MDP, Microsomal dipeptidase, RDP, Renal dipeptidase

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Galerie de données de validation

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  WB analysis using 12222-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 12222-1-AP (DPEP1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse liver using 12222-1-AP

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 12222-1-AP (DPEP1 Antibody) at dilution of 1:300 incubated at 4 degree celsius over night.

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Applications testées

• Résultats positifs en WB: cellules HepG2, cellules HEK-293, tissu hépatique de souris

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:5000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 3 publications below
• WB: See 4 publications below
• IHC: See 1 publications below
• FC: See 1 publications below

Informations sur le produit

12222-1-AP cible DPEP1 dans les applications de WB, FC, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, singe, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: DPEP1 Protéine recombinante Ag2907
• Nom complet: dipeptidase 1 (renal)
• Masse moléculaire calculée: 411 aa, 46 kDa
• Poids moléculaire observé: 46 kDa
• Numéro d’acquisition GenBank: BC017023
• Symbole du gène: DPEP1
• Identification du gène (NCBI): 1800
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

DPEP1(Dipeptidase 1) is also named as MDP, RDP and belongs to the peptidase M19 family. It is a glycoprotein that plays an important role in the regulation of leukotriene activity. DPEP1 converts lekotriene D4 to leukotriene E4.

Publications

Species	Application	Title
mouse,human	WB	Cell; Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver.; Authors - Saurav Roy Choudhury ; KO Validated
human	WB,FC	Sci Adv; Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.; Authors - Anne von Mässenhausen ; KD Validated
human	IHC	Sci Adv; Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury.; Authors - Arthur Lau
monkey		J Clin Invest; Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.; Authors - Arthur Lau
mouse	WB	Nat Commun; A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.; Authors - Yuting Guan ; KO Validated
mouse,human	WB	Int Immunopharmacol; Dipeptidase 1 promotes ferroptosis in renal tubular epithelial cells in diabetic nephropathy via inhibition of the GSH/GPX4 axis; Authors - Yan Li