Anticorps Recombinant de lapin anti-CEACAM1/CD66a

CEACAM1/CD66a Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241856H5

N° de cat : 98185-1-RR

Synonymes

Biliary glycoprotein D, Biliary glycoprotein 1, BGP-1, Bgp1, Bgp

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98185-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CEACAM1/CD66a Rabbit Recombinant Antibody (98185-1-RR, Clone: 241856H5) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD45R. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 98185-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CEACAM1/CD66a Rabbit Recombinant Antibody (98185-1-RR, Clone: 241856H5) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD45R. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98185-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98185-1-RR against Mouse CEACAM1/CD66a were performed. The affinity constant is below 1 pM.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98185-1-RR cible CEACAM1/CD66a dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: carcinoembryonic antigen-related cell adhesion molecule 1
• Masse moléculaire calculée: 57 kDa
• Symbole du gène: Ceacam1
• Identification du gène (NCBI): 26365
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530).

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