TSPAN6 Polyklonaler Antikörper

TSPAN6 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12293-1-AP

Synonyme

A15 homolog, T245, T245 protein, tetraspanin 6, Tetraspanin TM4 D, TM4SF6, TSPAN 6, TSPAN6

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Galerie der Validierungsdaten

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  WB analysis of mouse colon using 12293-1-AP

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 12293-1-AP (TSPAN6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis using 12293-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 12293-1-AP (TSPAN6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maus-Kolongewebe, Ratten-Kolongewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

12293-1-AP bindet in WB, ELISA TSPAN6 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TSPAN6 fusion protein Ag2964
• Vollständiger Name: tetraspanin 6
• Berechnetes Molekulargewicht: 245 aa, 28 kDa
• Beobachtetes Molekulargewicht: 25-30 kDa
• GenBank-Zugangsnummer: BC012389
• Gene symbol: TSPAN6
• Gene ID (NCBI): 7105
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TSPAN6 (also known as TM4SF6) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN6 gene is widely expressed, with high mRNA levels in liver, pancreas, kidney, and ovary (PMID: 9782095). TSPAN6 has been reported as a negative regulator of the RLR pathway by interacting with MAVS in a ubiquitination-dependent manner (PMID: 22908223).