TSLP Polyklonaler Antikörper

TSLP Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (1)

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen

8

Rezensionen (1)

Kat-Nr. : 13778-1-AP

Synonyme

thymic stromal lymphopoietin, TSLP

---

Galerie der Validierungsdaten

• 

  IHC staining of human kidney using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 13778-1-AP (TSLP Antibody) at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human kidney using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 13778-1-AP (TSLP Antibody) at dilution of 1:200 (under 40x lens).

• 

  IHC staining of human prostate cancer using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 13778-1-AP (TSLP Antibody) at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human prostate cancer using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 13778-1-AP (TSLP Antibody) at dilution of 1:200 (under 40x lens).

• 

  IHC staining of human testis using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human testis using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human testis using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human testis using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human spleen using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human spleen using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human spleen using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human spleen using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human lung using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human lung using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human lung using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human ovary using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human ovary using 13778-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary using 13778-1-AP (TSLP antibody) at dilution of 1:50 (under 40x lens).

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Nierengewebe, humanes Eierstockgewebe, humanes Hodengewebe, humanes Lungengewebe, humanes Milzgewebe, humanes Prostatakarzinomgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 2 publications below
• IHC: See 8 publications below

Produktinformation

13778-1-AP bindet in WB, IHC, ELISA TSLP und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TSLP fusion protein Ag4771
• Vollständiger Name: thymic stromal lymphopoietin
• Berechnetes Molekulargewicht: 15 kDa, 42 kDa
• GenBank-Zugangsnummer: BC016720
• Gene symbol: TSLP
• Gene ID (NCBI): 85480
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain, it mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Another isoform of this protein may act as an antimicrobial peptide in the oral cavity and on the skin (PMID: 24850429).

Publikationen

Species	Application	Title
human,mouse	IHC	Int Immunopharmacol; Hypoxia induces the production of epithelial-derived cytokines in eosinophilic chronic rhinosinusitis with nasal polyps; Authors - Meiping Zhang
human	IHC	Br J Dermatol; Elevations in Th2-initiating cytokines (IL-33, IL-25, TSLP) in lesional skin from Chronic Spontaneous ("Idiopathic") Urticaria.; Authors - A B Kay
human	IHC	J Immunol Res; Thymic Stromal Lymphopoietin Is Implicated in the Pathogenesis of Bullous Pemphigoid by Dendritic Cells.; Authors - Si-Zhe Li
human,mouse	WB,IHC	J Transl Med; TSLP promoting B cell proliferation and polarizing follicular helper T cell as a therapeutic target in IgG4-related disease; Authors - Hui Lu
human	IHC	Mediators Inflamm; Expression of Thymic Stromal Lymphopoietin in Immune-Related Dermatoses; Authors - Si-Zhe Li
human,mouse	WB,IHC	Int Immunopharmacol; Phellopterin alleviates atopic dermatitis-like inflammation and suppresses IL-4-induced STAT3 activation in keratinocytes; Authors - Xun Chen

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

---

FH

Becky (Verified Customer) (07-30-2018)

It would be great to have this ab stable at 4C. I only use 1uL at a time for ELISA, and storage is -20.

• Applications: Other (please state below),
• Primary Antibody Dilution: 1ug/mL
• Cell Tissue Type: recombinant human TSLP protein coated at 2ug/mL